Representatives from the City of Detroit, Michigan, meant well, but nearly put lives in danger recently with plans to demolish around 3,000 dilapidated homes and other buildings in a blighted area. The project, whose ultimate goal was to remove 10,000 dangerous abandoned buildings over the next four years and eliminate risks like collapse, fire and disease, was featured in the local newspaper, the Detroit Free Press. As it turned out, someone from the state Department of Natural Resources and Environment was reading, and the story raised a red flag.

After a quick investigation, DNRE spokesman Robert McCann told the Free Press the agency discovered the City had not completed required asbestos inspections on the properties scheduled for demolition. The City also had not notified the state – which is required by law – of the planned demolition. The planned project was halted April 5, and City officials met with DNRE representatives to learn what they should do.

According to the Free Press, representatives from the City said they were unaware they were violating any federal regulations, and said the City has not had a history of inspecting buildings for the presence of asbestos before demolition under past administrations. The current Mayor is Dave Bing.

Some demolition occurred before DNRE officials were able to call a halt; however, subsequent asbestos testing did not find any asbestos present. The project is under the direction of the City’s Buildings and Safety Engineering Department. The houses planned for demolition are located in southwest Detroit. The City still plans to demolish 3,000 structures by the end of this year, and 10,000 structures during the next four years.

Federal regulations require that businesses or individuals planning demolition first test the structure for the presence of asbestos, remove any asbestos that is found using approved abatement procedures to ensure the safety of workers and the public, and provide a 10-day notice to the DNRE before beginning demolition. Violations could incur fines of up to $27,500 per day, and jail time. It was not noted in the Free Press story if the City is in danger of being prosecuted for its violations.

However, public interest in the story did raise awareness about the dangers of asbestos exposure, which can result in mesothelioma, a deadly cancer that affects the lining of the chest and lungs, the lining of the abdomen, or the lining of the heart. As a result of reader interest, the newspaper published a helpful Q&A about asbestos exposure the following day.

A study published today in The New England Journal of Medicine reveals that Fire Department of New York (FDNY) firefighters and emergency medical services (EMS) workers who responded to the 9/11 attacks at the World Trade Center have suffered significant, persistent declines in lung functions. According to the report, exposure to World Trade Center dust created when the towers collapsed led to “large declines” in lung functions for FDNY rescue workers during the first year, and that “the declines were persistent, without recovery over the next 6 years, leaving a substantial proportion of workers with abnormal lung function.”

The study included 12,781 workers who were present at the WTC site between Sept. 11, 2001 and Sept. 24, 2001, which is 91.6 percent of the workers that were present. The report notes that the event exposed the workers – as well as those living and working in the surrounding area – to a dense cloud of pulverized building materials and chemical byproducts, including pulverized glass and cement, insulation fibers including asbestos, and toxic chemicals.

According to a report in The New York Times that summarizes the study findings, this is the first study to document long-term harm in a large group of firefighters and emergency medical workers who worked at Ground Zero. All of the subjects of the study had had previous lung function tests, providing a baseline for the study.

The study was authored by Dr. David J. Prezant, chief medical officer in the Office of Medical Affairs at the New York City Fire Department. The study was approved by the institutional review board at Montefiore Medical Center.

Results of the study revealed that firefighters, who had heavier exposure to dust by the nature of their work had greater first-year declines than EMS personnel, especially for firefighters who were present in the morning on 9/11, when the dust cloud was most intense after the buildings fell. However, researchers noted they were surprised to see “little or no recovery of average lung function during the 6-year follow-up period.” In fact, they noted continued decline in lung function among the study groups.

Normally, the study notes, “smoke inhalation during firefighting causes relatively mild and reversible respiratory impairment.” Additionally, according to the report, long-term effects of firefighting on pulmonary function also are normally mild.

The average loss of lung function for 9/11 rescue workers is about 10 percent. Most of the loss occurred within the first year after 9/11 exposure, with little or no subsequent recovery.

Thousands of workers injured at Ground Zero have been fighting for compensation from the City of New York. Last month about 10,000 plaintiffs reached a settlement agreement totaling $657.5 million, but a judge rejected the settlement shortly afterward, saying it did not provide enough compensation for the plaintiffs. The matter is now back in negotiations, and a new hearing is set for Monday, according to the Times.

Montgomery Mayor Todd Strange presented a proclamation today declaring April 1-7 as Asbestos Awareness Week in the city of Montgomery, Alabama. The proclamation supports National Asbestos Awareness Week, as established by Senate Resolution 427.

It is the purpose of Asbestos Awareness Week to raise public awareness about the prevalence of asbestos and the dangers of asbestos exposure in the United States and around the world. Microscopic asbestos fibers can be inhaled or ingested, and imbed themselves in the body where they can cause diseases such as asbestosis, a severe scarring of the lungs, and mesothelioma, a deadly cancer that can affect the chest and lungs, the abdomen or the heart.

The U.S. Congress has recognized a National Asbestos Awareness Day or Week for the past six years. The awareness effort is a project of the Asbestos Disease Awareness Organization (ADAO), which is the largest organization in the United States serving as the voice of asbestos victims. The ADAO lobbies for the complete ban of asbestos and asbestos-containing products in the U.S. It is estimated that within the next decade 100,000 workers around the world will die of an asbestos-related disease. That equals 30 deaths each day.

For more information, visit ADAO online.

Bionomics, an Australian biotechnology company, has announced the beginning of Phase II clinical trials for its vascular disrupting agent BNC105 as a treatment for mesothelioma. The company announced its plans to test the drug on mesothelioma patients in December 2009. It will partner with the Australasian Lung Cancer Trials Group (ALTG) and the NHMRC (National Health and Medical Research Council) Clinical Trial Centre.

The clinical trial involves 60 patients at 12 centers in Australia.It is a single arm, unblinded study for patients with mesothelioma who have progressed on platinum/pemetrexed chemotherapy. BNC105 will be administered on days 1 and 8 of 21-day cycles. Treatment will continue until disease progression. The primary objective is to determine the tumor response rate.

Principal investigator for the trial is Dr. Anna Nowak, professor at the Faculty of Medicine, University of Western Australia and consultant medical oncologist at Sir Charles Gairdner Hospital. According to information on the company’s web site, Bionomics has already commenced Phase II testing of the anti-cancer properties of BNC105 in renal cancer in the United States. The commencement of this Phase II trial follows a successful BNC105 Phase I clinical trial in patients with advanced cancers at the Peter MacCallum Cancer Centre, the Western Hospital, Austin Health and the Royal Melbourne Hospital.

Dr. Nowak says, “Mesothelioma remains a substantial problem in Australia and other parts of the world. An early clinical trial of BNC105 suggested some promise in mesothelioma. This Phase II trial will provide hope and an opportunity to participate in a research study for people with mesothelioma who do not have other options for treatment.”

Dr. Deborah Rathjen, CEO and Managing Director of Bionomics, says the company expects to report interim results of this study in mesothelioma patients in early 2011.

In 2005, Bionomics reports there were 597 new cases of mesothelioma diagnosed in Australia and in 2006 there were 486 deaths attributed to mesothelioma.

More information about the clinical trial is available online. Inquiries may be directed to:

Bionomics Limited
Dr Deborah Rathjen
CEO & Managing Director
+61 8 8354 6101 / 0418 160 425
drathjen@bionomics.com.au

Monsoon Communications
Rudi Michelson
+61 3 9620 3333

This week the Mesothelioma Applied Research Foundation (Meso Foundation) alerted me through a link on their web site to an update in the ongoing mesothelioma study in Minnesota. We have been following this study, which is investigating the high incidence of mesothelioma among Iron Range miners in that state. According to a report in the Duluth News Tribune, the study has identified four new cases of mesothelioma.

The five-year study is being directed by the University of Minnesota and the Minnesota Department of Health, and funded by a $4.9 million grant from the Minnestoa state legislature. The new cases bring the total number of former miners diagnosed with mesothelioma to 63.

Mesothelioma has traditionally been linked exclusively to asbestos. However, an investigation into the link between taconite mining – which takes place in what is known as Minnesota’s Iron Range, – began when state health officials noted an unusually high incidence of mesothelioma occurring in taconite mine workers. Mesothelioma occurs at twice the expected rate in the Iron Range.

As part of the study, researchers are screening workers and their immediate families. To date, they have interviewed about 1,000 people, and would like to double that number.

Taconite is an iron-bearing, flint-like rock. Processed taconite pellets are used in the steel making industry.  To process taconite, the ore is ground into a fine powder, the iron is separated from the waste rock using strong magnets and the powdered iron concentrate is combined with bentonite clay and limestone and rolled into pellets. The Mesabi Iron Range region of Minnesota is a major taconite production area.

More information is available at the project’s official web site for Minnesota Taconite Workers Health Study.

Pictured above are processed taconite pellets. Source: Wikipedia

Traditionally, April 1 has been designated by the Asbestos Disease Awareness Organization (ADAO) as Asbestos Awareness Day. The day has been officially recognized by U.S. Congress proclamation for the past six years. In recent years, the awareness effort has expanded, and now the first week of April is officially designated as Asbestos Awareness Week. The theme for the awareness week is “Knowledge is stronger than asbestos.”

On March 26, the ADAO praised the U.S. Senate for passage of the sixth annual resolution establishing National Asbestos Awareness Week. Senate Resolution 427 also urges the Surgeon General to warn and educate Americans about the severe hazards of asbestos exposure.

The ADAO is the largest organization in the United States serving as the voice of asbestos victims, and lobbies for the complete ban of asbestos and asbestos-containing products in the U.S. Asbestos exposure is linked to the development of a number of diseases, including asbestosis, a severe scarring of the lungs; and mesothelioma, a deadly cancer that affects the lining of the lungs and chest, abdomen or the heart. According to statistics compiled by ADAO, in the next decade it is estimated that 100,000 workers around the world will die of an asbestos-related disease. This equals 30 deaths each day.

ADAO co-founder and CEO Linda Reinstein said, “We are grateful to the U.S. Senate for unanimously passing S. Res. 427 that will increase public awareness about asbestos, a known human carcinogen. For the past six years, ADAO has seen that a week of awareness enables agencies, institutions and organizations to promote regulatory compliance and enforcement. Americans deserve and want to know how to prevent asbestos in their homes or in the workplace.”

Asbestos Awareness Week 2010 will be held April 1-7. Visit ADAO online for more information about asbestos and its commercial use; how to prevent exposure in homes, schools and workplaces; early warning symptoms and medical treatment options; and to find out more about why asbestos is still not a banned product in the U.S. and how it is used in common household products.

UK Justice Secretary Jack Straw

Earlier this month, Chris Hahn, executive director of the Mesothelioma Applied Research Foundation (Meso Foundation) expressed his support for the recent announcement from the UK that it plans to not only endorse compensation for mesothelioma victims, but to promote research and treatment. In a news release, Hahn praised the U.K. for its recognition “that society’s obligation and moral responsibility to remedy the tragic legacy of decades of asbestos use requires funding research to develop effective medical treatments.” Then, he asked the all-important question: “Will the United States follow?”

Hahn’s praise and plea followed remarks by the U.K.’s Lord Chancellor and Secretary of State for Justice, Jack Straw, who has been outspoken about the government’s role in caring for workers harmed by asbestos on the job.  Straw issued a statement Feb. 25, 2010, in response to an ongoing debate over the government’s decision on the question of compensation for pleural plaques.

Although pleural plaques, which are small areas of fibrosis in the pleura of the lung caused by asbestos exposure, indicate that a person has been exposed to asbestos, they generally do not cause any significant change in lung function. As a result, the Law Lords on Oct. 17, 2007 determined that people who have pleural plaques, but no other asbestos-caused illness, are not eligible for any compensation for medical treatment or other financial claims. The debate over pleural plaques sparked a national debate about asbestos disease.

Although subsequent research did not provide enough evidence to overturn the Law Lords’ ruling, it has provided significant information about asbestos disease, including mesothelioma and lung cancer. The government also is establishing a number of policies to make it easier for those who are diagnosed with mesothelioma or serious asbestos disease to receive compensation more quickly. Additionally, the research has encouraged the UK government to take a stronger stand on mesothelioma research and treatment.

According to Straw’s statement, “The fact that the UK has one of the highest rates of death from mesothelioma in the world is a legacy of our industrial heritage and the part that asbestos played in it. Just as the UK was a global leader in the asbestos industry, we must now become a global leader in research into asbestos-related disease.”

The government of the UK is calling for the creation of a National Centre for Asbestos-Related Disease, which will be a “collaborative network of funded researchers whose core purpose would be to advance medical research into the prevention, cure and alleviation of asbestos-related disease – primarily mesothelioma,” according to Straw. He said the insurance industry has pledged £3 million toward this research effort.

Benefits of such a concentrated and cooperative research and treatment program would not only benefit mesothelioma patients, but also would significantly reduce the costs of litigation, death and disability benefits, and health care costs, Hahn points out.

“This is exactly what the Mesothelioma Applied Research Foundation has been urging in the United States the past ten years,” Hahn says. “Mesothelioma and other asbestos-related diseases are a fundamental problem of social justice. And a just solution to that problem requires medical research to develop effective treatments to end the suffering and save lives. It is encouraging to see that the U.K. is getting it; we hope the U.S. will catch up soon.”

Read Hahn’s statement.

For more information, visit the Meso Foundation online at www.curemeso.org.

Linda Reinstein, co-founder of the Asbestos Disease Awareness Organization (ADAO) recently had the opportunity to participate on a panel discussion as part of an Occupational Safety & Health Administration (OSHA) public meeting. The event, held March 4 and called “OSHA Listens” was designed to solicit comments and suggestions from OSHA stakeholders on key issues facing the agency. As a representative of ADAO, Ms. Reinstein was able to address OSHA leaders about the urgency and importance of a complete ban on asbestos. The meeting was held in Washington, D.C.

The program was designed to help OSHA learn about key areas that will enhance and encourage the efforts of employers, workers and unions to identify and address workplace hazards. The agency asked for feedback about emerging unaddressed health and safety issues, how to improve efforts to engage stakeholder in program and initiatives, and for help in identifying priorities.

Ms. Reinstein, who lost her husband Alan to mesothelioma in 2004 as a result of his exposure to asbestos in the workplace, was joined on the panel by others who had lost loved ones to workplace hazards. Overseeing the panel discussion was David Michaels, Assistant Secretary, OSHA; and Deborah Berkowitz, Chief of Staff, OSHA.

“ADAO urges OSHA to move from helping to control to preventing asbestos exposure, and we urge you to help disseminate other government agencies’ information … to increase awareness and support for best practices and encourage compliance,” Reinstein told the panel. She pointed out that OSHA’s own web site estimates 1.3 million employees in construction and general labor have faced “significant asbestos exposure.”

Reinstein also took the opportunity to ask OSHA’s leaders to support pending legislation that calls for a complete ban of asbestos in the U.S.

“Clearly, one life lost to asbestos disease is tragic, but hundreds of thousands of lives lost is unconscionable,” she said. “OSHA has the opportunity – and the responsibility – to protect Americans from these preventable diseases. We count on you to push this forward, and we would encourage and ask that Secretary (of Labor Hilda L.) Solis support asbestos ban legislation to prevent asbestos-caused diseases to protect workers and their families on behalf of the tens of thousands who have lost their life.”

Transcripts of the meeting are available on the OSHA web site.

A web cast of the meeting, including Panel 1, which features Ms. Reinstein, also is available by visiting OSHA online.

A story published by the New York Times reports thousands of rescue and cleanup workers who were exposed to the toxic air at Ground Zero after the 9/11 tragedy at the World Trade Center have reached a settlement agreement with the city over damage to their health. According to the Times, the city has agreed to pay out up to $657.5 million to about 10,000 plaintiffs in the case.

The settlement agreement has been in the works for about two years, taking place among a great deal of confusion and disagreement about the city’s responsibility for injured workers. The city had claimed it was immune because injuries occurred during a national emergency or civil defense situation. However, injured workers and their families argued they were employed by the city and entitled to compensation as they would be for any injury incurred on the job.

According to the Times report, 95 percent of the plaintiffs in this case must accept the terms of the settlement for it to take effect. Each plaintiff’s case will then be examined individually to determine how much compensation that person will receive, which lawyers estimate could run anywhere from a few thousand dollars to as much as $1 million. Individual compensation will depend on the severity of illness and level of exposure to contaminants at the World Trade Center site.

A variety of health screening and tracking programs were established in the days and months following the September 11 tragedy. Workers and others who simply lived and worked near the disaster site began complaining of a variety of illnesses, especially respiratory problems. There is an official World Trade Center Medical Monitoring and Treatment Program, as well as studies conducted by the New York Fire Department and other organizations.

Some health problems presented immediately following exposure to the site, such as respiratory distress, while others are only just showing up in those who worked at the site. It is now known that the Ground Zero site was contaminated with asbestos at levels at least two times higher than the Environmental Protection Agency’s “safe” level. Because of the long latency period between exposure to asbestos and the development of mesothelioma – an average of between 10 and 50 years – the true effect of asbestos exposure may not be known for years to come.

Some of the plaintiffs involved in the current settlement are not yet ill, but fear they will develop illnesses in the future as a result of their exposure to the toxins like asbestos. According to the Times, the settlement provides a $23.4 million insurance policy to cover possible future claims.

Not three months ago, on Dec. 31, it was announced that football and television star Merlin Olsen had been diagnosed with mesothelioma. Today I learned that he has passed away, a victim of this horrible disease that lies in wait to kill. He was only 69 years old.

Olsen was a star defensive lineman for the Los Angeles Rams football team, who went on to a television acting career. He played Jonathan Garvey on the series Little House on the Prairie and was the title character of Father Murphy. He also appeared on Fathers and Sons and Aaron’s Way, and filled the role of sportscaster at both CBS and NBC.

Online celebrity news magazine TMZ broke the news in December that Olsen and his family had filed a lawsuit against several companies, including NBC Studios, NBC Universal and 20th Century Fox Film Corporation, claiming they were responsible for exposing him to asbestos, which causes mesothelioma. Also named in the suit are Sherwin Williams and Lennox Industries, whose products Olsen says he was exposed to during jobs in his youth.

Read his obituary in the Los Angeles Times.

On December 8, 2009, his alma mater, Utah State University, where he was selected twice as an NCAA All-American, among other honors, announced it would name its football field after him – Merlin Olsen Field. How truly sad that he will never see a team take the field that now bears his name. Watch the tribute video created by the university at the announcement:

What a sad loss of a man who truly seemed to care genuinely for others, for his family and his community. He will be genuinely missed.