A story published by the New York Times reports thousands of rescue and cleanup workers who were exposed to the toxic air at Ground Zero after the 9/11 tragedy at the World Trade Center have reached a settlement agreement with the city over damage to their health. According to the Times, the city has agreed to pay out up to $657.5 million to about 10,000 plaintiffs in the case.

The settlement agreement has been in the works for about two years, taking place among a great deal of confusion and disagreement about the city’s responsibility for injured workers. The city had claimed it was immune because injuries occurred during a national emergency or civil defense situation. However, injured workers and their families argued they were employed by the city and entitled to compensation as they would be for any injury incurred on the job.

According to the Times report, 95 percent of the plaintiffs in this case must accept the terms of the settlement for it to take effect. Each plaintiff’s case will then be examined individually to determine how much compensation that person will receive, which lawyers estimate could run anywhere from a few thousand dollars to as much as $1 million. Individual compensation will depend on the severity of illness and level of exposure to contaminants at the World Trade Center site.

A variety of health screening and tracking programs were established in the days and months following the September 11 tragedy. Workers and others who simply lived and worked near the disaster site began complaining of a variety of illnesses, especially respiratory problems. There is an official World Trade Center Medical Monitoring and Treatment Program, as well as studies conducted by the New York Fire Department and other organizations.

Some health problems presented immediately following exposure to the site, such as respiratory distress, while others are only just showing up in those who worked at the site. It is now known that the Ground Zero site was contaminated with asbestos at levels at least two times higher than the Environmental Protection Agency’s “safe” level. Because of the long latency period between exposure to asbestos and the development of mesothelioma – an average of between 10 and 50 years – the true effect of asbestos exposure may not be known for years to come.

Some of the plaintiffs involved in the current settlement are not yet ill, but fear they will develop illnesses in the future as a result of their exposure to the toxins like asbestos. According to the Times, the settlement provides a $23.4 million insurance policy to cover possible future claims.

One of the many mesothelioma community members on Facebook posted a question today about a clinical trial being conducted at the Mesothelioma Center, located at New York-Presbyterian Hospital. MyMeso discussed this clinical trial in a July post. The clinical trial is a program of targeted radiation and chemotherapy protocol for pleural mesothelioma, which is a cancer of the lung’s lining almost always caused by asbestos. In response to the Facebook thread, meso survivor and awareness advocate (read: warrior) Debbie Brewer, who many of you know from her story and updates here (thanks Debbie!), mentioned a similar study currently ongoing in Australia.

Debbie provided a link to a story published in November 2009 by ABC News that outlines the work of specialists at Austin Health Centre in Victoria. The treatment, spearheaded by Dr. Malcolm Feigen, a radiation oncologist at the Centre, uses high doses of radiotherapy, concentrated on specific areas of the lining of the lungs to target mesothelioma tumors.

According to the ABC report, 13 patients participated in a pilot program to test this new targeted radiotherapy treatment. Most had some surgery prior to the radiotherapy treatment, and some also had chemotherapy before or after the treatment, although Dr. Feigen believes the patients showed the most benefit primarily as a result of the radiotherapy regimen.

Participants in the U.S. clinical trial at the Mesothelioma Center receive a multi-modality therapy that incorporates surgery, chemotherapy and radiation therapy in combination.

Listen to the interview with Dr. Feigen about the Australian research, which was broadcast on ABC’s AM morning current affairs program.

A December report by the New York Times revealed that Sen. Max Baucus (D-Montana) has inserted language into the government’s proposed health care legislation that would provide coverage specifically for people exposed to asbestos in Libby, Montana. According to the report, language in the bill would expand Medicare coverage to vicitims of “environmental health hazards.”

According to the Times, the language is even more precise, calling for coverage for “individuals exposed to environmental health hazards recognized as a public health emergency in a declaration issued by the fedearl government on June 17.” This declaration and date, of course, coincides with the U.S. Environmental Protection Agency’s designation of Libby as a Public Health Emergency area.

The Times quotes Baucus as saying the language is not only intended for the people of Libby, but for anyone in the future whose town is affected by a similar tragedy that affects the health and well-being of its people. He said the legislation would provide a safety net to “help people when they need it most.”

Both the U.S. House of Representatives and the U.S. Senate passed their versions of the health care reform bill last year. It is now up to the 111th Congress as a whole to reconcile the two bills so that they may be presented to President Obama for his signature.

Congressional leaders say they hope to accomplish this by the end of January.

Today, millions of Americans turned their thoughts to where they were and what they were doing on this date eight years ago, when they heard of the terrorist strike on the World Trade Center in New York City. They mourn for loved ones lost in the attacks, and gather their resolve to pull together as a nation as we did in the days following the attacks. But for many, the horror, the fear and the dying continues. For the brave first responders, who arrived while the buildings burned and stayed through their collapse and through the heartbreaking months that followed during cleanup, the disaster has created lingering illness, debilitating respiratory diseases and cancers including mesothelioma.

A CBS News investigative report spoke with individuals and families coping with this second disaster, a disaster that robs them and their loved ones of health and quality of life. Rescue workers, very few wearing any type of special gear, toiled day after day in dusty clouds of toxins including asbestos, jet fuel, mercury, lead and pulverized cement and glass. According to the CBS News report, health officials say such multi-chemical exposure as these workers experienced is “unprecedented.”

A variety of health screening and tracking programs were established in the days and months following 9/11/2001, when workers and even people who simply lived and worked near the disaster site began complaining of a variety of illnesses, particularly respiratory distress. To date, according to the CBS report, about 43,000 people have been physically screened for 9/11-related health issues, 28,000 are participating in the official World Trade Center Medical Monitoring and Treatment Program, and an additional 18,000 people in a similar program operated by the New York Fire Department.

Many 9/11 responders are angry, saying they have to wade through mounds of regulations, restrictions and other roadblocks to fight for access to care and compensation. Many who die are not classified as technically having died “in the line of duty,” and their families are denied those benefits.

Physicians say it is difficult to definitively link health conditions to 9/11 exposures because of the wide variety of toxins present on the site, and the varying levels of exposure among workers to amounts and types of chemicals and other substances. Some trouble signs presented immediately, such as respiratory distress, while others, such as immune system cancer multiple myeloma, and colon cancer, are now showing up in responders age 45 and younger.

Some diseases could take even longer to develop. Mesothelioma, a deadly cancer that affects the lining of the lungs, abdomen and/or heart, is a result of asbestos exposure. It is now known that the 9/11 site was contaminated with asbestos at levels at least two times higher then the EPA’s “safe” level. The latency period for mesothelioma averages between 10 and 50 years, so the effect of this asbestos exposure may not be known for years to come.

How tragic that one of the most tragic days in recent American history should be borne the hardest by those who were bravest, those who dedicated their lives to caring for their fellow man, who rushed into the danger zone while others rushed away. My heart goes out to these brave souls, and I pray that they are not forgotten.

There is a link below to the comprehensive CBS News report about this. There is a wealth of information at this site, including video interviews with 9/11 responders, medical reports about 9/11 health issues, and links to resources and information about World Trade Center responder health programs and studies. I urge you to add a comment at the CBS web site voicing your support for more programs to help these brave folks.

Source: CBS News

I’ve posted about several mesothelioma fund-raising and awareness events during the past month, happening in places like Texas, New York, Florida and Pennsylvania. Activities have ranged from bike rides to walks and even a bowl-a-thon. Proceeds from these events have gone toward mesothelioma research, through the Mesothelioma Applied Research Foundation (MARF), or will benefit an individual, like Shanna Kurtz, in her personal battle against mesothelioma.

Today I heard from two people who are looking for ways to help raise awareness of mesothelioma and funds for research. One lives in California and the other in New York. If you know of any events in these areas in the coming weeks, please email us at myMeso – you can just click that green “Contact Us!” button on the home page, or you can email me directly at wendi.lewis@beasleyallen.com.

Also, if you send us information about an event, please include information about where the proceeds will go (either to an individual or an organization) and let us know how people can donate even if they cannot attend the event. Many people in the meso community will still want to help, even if they aren’t able to travel to your area to participate.

I look forward to helping you get the word out about your mesothelioma awareness event!

A friend recently forwarded me a link to a web site that features an ad touting the wonders of asbestos for fire protection, highlighted by a photo of the World Trade Center’s twin towers. The ad was produced in 1981, so it’s not a matter of bad taste, just creepy in light of the September 11 disaster, and ironic because the presence of asbestos in the towers has been a source of health problems for the disaster’s first responders, among the many dangerous toxins released when the buildings collapsed.

The ad references fire alarms, most likely referring to a Feb. 13, 1975 fire that broke out on the 11th floor of the North Tower. But it hits a little too close to home after the events that would take place a little over 25 years later.

On the anniversary of the 2001 tragedy last year, we discussed the ongoing studies being conducted by the New York City Department of Health and Mental Hygeine on the effects of exposure to the dust released in the catastrophe. The study included close to 5,000 samples of airborne asbestos collected by the EPA in lower Manhattan between Sept. 11, 2001 and Jan. 22, 2002, many of which exceeded “safety” standards.

It is ironic that the ad for asbestos prominently features the tag line “when life depends on it, you use asbestos.”

In 1981, the asbestos industry was already under scrutiny for the link between asbestos and mesothelioma, a deadly cancer that affects the lining of the lungs, and sometimes the stomach and/or heart. Most recent studies by the National Cancer Institute show that people with even brief exposure to asbestos are at risk. There is no “safe” level of asbestos exposure.

We recently have added a petition to this site urging the U.S. Congress to finally support a total ban of asbestos in the United States, and to provide funding for mesothelioma research. Please sign the petition, and add your voice to this fight.

The New York State Department of Health has been collecting information about deaths among World Trade Center responders, recovery workers and volunteers since shortly after the tragedy.

As of June 2008, the program had identified 382 people who worked at the WTC site who had passed away, and confirmed 204 causes of death, including 30 deaths resulting from respiratory and intrathoracic organ disease. In an updated report released in December 2008, the number of deaths of people who worked at the WTC had jumped to 713 people, with 548 confirmed causes of death. The number of deaths attributed to respiratory and intrathoracic organ disease is noted at 56, accounting for 14.1 percent of the deaths.

Of course, these numbers are general, and not specifically linked to asbestos inhalation, but the report does note that 30.2 percent of the confirmed causes of death of people who worked at the WTC are releated to “exposure to harmful substances or environments,” and 27.3 percent specifically related to “ingestion of substance.”

If you live in the area of East Meadow, New York, on Long Island in Nassau County, there is still time to register for the Fourth Annual 5k Walk for Hope, which is set for this Sunday, April 19. The event will raise funds for the Mesothelioma Applied Research Foundation (MARF) and raise awareness of mesothelioma and the dangers of asbestos.

The 5k Walk for Hope was established in 2006 by Janice Malkotsis, who lost her father, Joseph Lombardo, to mesothelioma in 2005. Mr. Lombardo was diagnosed with peritoneal mesothelioma in 2004 and his family suffered with him as they watched him lose his fight to this deadly cancer, caused by exposure to asbestos.

Janice says she promised her father in his final weeks that she would work to educate people about mesothelioma, which is still largely unknown and unreported in the United States. Through MARF, Janice partnered with Erica Iacono, who also lost her father to mesothelioma, and the two created the 5k Walk for Hope. Together, they’ve raised nearly $50,000 for mesothelioma research through this event. They also are sponsored by Joe Fox of Belluck & Fox, LLP, who represented Mr. Lombardo before his death.

The 5k Walk for Hope will be held at Eisenhower Park in East Meadow, NY, with sign-in at 9 a.m. and the the walk beginning at 10 a.m. Registration is $15. Download the online registration form.

If you are unable to attend the walk, but would like to support this effort, you can send a donation that will go to MARF. The Mesothelioma Applied Research Foundation is the nonprofit collaboration of patients and families, physicians, advocates and researchers dedicated to eradicating the life-ending and vicious effects of mesothelioma.

You can send your donation to the following address:

5k Walk for Hope
c/o Janice Malkotsis
130 Taft Avenue
Merrick, NY 11566
(checks should be payable to 5k Walk for Hope)

The criminal trial against W.R. Grace & Co. is continuing this week at the Russell Smith federal courthouse in Missoula, Montana. The company, along with former company officials, are charged with conspiracy, obstruction of justice and knwoing endangerment of the Clean Air Act. The government says Grace knew its vermiculite mine in Libby, Montana, produced dangerous asbestos that put the health of its workers and the nearby townspeople at risk.

Hundreds have died in Libby as a result of exposure to asbestos, suffering a number of serious asbestos related diseases including asbestosis, a serious scarring of the lungs, and mesothelioma, a deadly cancer that affects the lining of the lungs and/or the abdomen. In 1999 an investigation revealed widespread asbestos contamination in Libby, and the Environmental Protection Agency began an effort to clean up the town, which continues today.

The story is receiving coverage from a number of media sources. The New Yorker called this the “most significant environmental criminal trial in American history.”

Early on, Judge Donald Molloy sparked anger in Libby residents when he ruled that victim witnesses would not be allowed to sit in on the trial. Regular myMeso reader and contributor Mike Crill, a longtime resident of Libby who has lost several family members to asbestos disease and suffers from asbestosis himself, was quoted in the Montana Kaimin when he and other Libby residents staged protests outside the courthouse.

The Kaimin quotes Crill as saying, “So much for freedom of speech, huh? Especially when you’re the victims and you’re being told that you’re not the victims.”

There is a great blog site by writer Tristan Scott, who also is doing a comprehensive series on the trial for The Missoulian, that is detailing the goings on at the Grace criminal trial. The blog, Cops and Courts, which bills itself as a “criminal justice blog” even has transcripts from court proceedings.

The Missoulian also has a special site set up with lots of archival information about W.R. Grace and Libby, Montana, as well as facts about asbestos, vermiculite mining and more. The site includes videos and slideshows as well.

Photo courtesy of Cops and Courts blog.

As he lay dying of mesothelioma in a Miami area intensive care unit, successful attorney, Democratic Party activist and philanthropist Milton M. Ferrell, Jr., recorded a video deposition against asbestos manufacturers, according to a report in the Miami Herald. Ferrell passed away just a little over 15 hours later, on Saturday, Nov. 15.

Recorded with literally his last breaths, the video deposition names the Big Three automakers, along with specific brake manufacturers, accusing them of marketing “unreasonably dangerous” products and failing to warn people about the asbestos danger inherent in the products, the Herald reports. According to the paper, Ferrell worked on automobiles as a young man, and it is suspected he inhaled asbestos fibers while working on brakes.

Ferrell, who was listed among the country’s top 100 attorneys in 2006, began suffering what his wife described as “flu-like symptoms” about two years ago, the Herald reports. He was diagnosed with mesothelioma in Spring 2008 and had his left lung removed in May. But the cancer spread to his brain, stomach, hip and his right lung. He rejected pain medication on his deathbed in order to record his deposition, according to the Herald.

Among his achievements, he founded his own firm, Ferrell Law, with offices in Miami and New York. Active in Democratic politics, he was a major fundraiser for President Bill Clinton and served as John Kerry’s Florida finance chairman in 2004 during Kerry’s bid for the White House.

Funeral services are set for Friday, Nov. 21, at 11 a.m. at Trinity Episcopal Cathedral in Miami. The family requests in lieu of flowers that donations be made to the International Mesothelioma Program at Brigham and Women’s Hospital in Boston. Ferrell is survived by his wife Lori, son Morgan and daughter Whitney.

A report recently published in Cell Cycle supports the preferential effectiveness of ONCONASE toward tumor cells, and underlines the effectiveness of the drug in treating malignant mesothelioma. Cell Cycle is a scientific journal that focuses on molecular aspects of cancer research, and which is dedicated to research on the cell cycle and cancer.

The report is the result of collaborative research conducted at the Brander Cancer Research Institute and the Department of Pathology at New York Medical College, in conjunction with the drug manufacturer, Alfacell.

The new study provides further evidence of the impact ONCONASE has on the RNAi mechanism, said Alfacell CEO Kuslima Shogen in a company news release. Shogen said it also provides evidence as to why ONCONASE helps sensitize cells to other antitumor agents.

According to the release, “The study demonstrated that silencing the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) gene (an abundant and ubiquitously expressed housekeeping gene) in human lung adenocarcinoma A549 cells by siRNA was effectively prevented by ONCONASE. While transfection of cells with GAPDH siRNA reduced expression of this protein by nearly 70 percent, the expression was restored in the cells exposed to ONCONASE for 48 or 72 hours. The data thus provide evidence that one of the targets of ONCONASE (ranpirnase) is siRNA.”

Results of ONCONASE Phase III clinical trials, “demonstrate significant efficacy in patients with malignant mesothelioma that failed prior chemotherapy,” according to Alfacell information. The drug utilizes a proprietary ribonuclease (RNase) technology that targets cancer cells while sparing normal cells.