Posts Tagged ‘talc pleurodesis’

Pleurodesis needs more research into patient outcomes, study finds

22 Jan 2018 by under Research/Treatment

upper body 944557 960 720 100x100 Pleurodesis needs more research into patient outcomes, study findsFluid buildup in the chest cavity is a common symptom of . The excess fluid, known as , is linked to shortness of breath, greatly decreasing patient comfort as they fight the deadly cancer. Pleurodesis, a procedure to prevent the future accumulation of fluid, is often used as a treatment method, but a new study highlights how the risks associated with the procedure are not as well-known as popularity of the procedure would suggest. (more…)

Mesothelioma clinical trial in UK recruiting participants

19 Aug 2009 by under News, Research/Treatment

A clinical trial for patients with malignant mesothelioma is currently recruiting participants. The trial is sponsored by Papworth Hospital in the , although it is open to any mesothelioma patient that meets the criteria. This study will evaluate video-assisted surgery to see how well it works compared with talc pleurodesis in treating patients with malignant mesothelioma.

According to information on, a service of the U.S. National Institutes of Health, this is a randomized phase III trial. Video-assisted surgery removes part of the tissue layer covering the inside of the chest cavity, which researchers think may be effective in treating pleural effusion and cause less damage to normal tissue. Talc pleurodesis may keep fluid from building up in the chest cavity. It is not known at this time which thereapy is more effective.

The primary objective of this study, as stated in the project outline, is to compare the effectiveness of these two modes of treatment in terms of 1-year survival, in patients with suspected or proven malignant mesothelioma.

Secondary goals of the study include comparing the control of pleural effusion, comparing procedure-related complications, comparing symptoms and quality of life of these patients at 3, 6 and 12 months after treatment, comparing the length of hospital stay, the exercise tolerance level of these patients at 3, 6 and 12 months after treatment, and to determine the cost to the health service, in terms of resources used for procedures, hospital bed usage and cost of primary and secondary care over 12 months.

Recruiting locations in the UK are Basildon University Hospital, Gelnfield Hospital (Leicester), Guy’s Hospital (London), Papworth Hospital (Cambridge) and Royal Hallamshire Hospital (Sheffield). Principal investigator for the study is Robert Winter, MD, Papworth Hospital.

This study is identified in the U.S. at by ID number NCT00821860.

For contact and recruiting information, visit the information page at